Web025670 STOCK Myl1 tm1.1(cre/ERT2)Lepr /J These mice express tamoxifen-inducible Cre recombinase under the direction of the Myl1 promoter in fast skeletal muscle. 025670 - … WebCre) model has suggested that while Sirt6 is critical for glucose homeostasis and insulin sensitivity it ... Myl1-Cre) and Sirt6 transgenic (Tg) mice, with a particular focus on mitochondrial biogenesis. We also treated mice with a …

Inducible Cre transgenic mouse strain for skeletal muscle

Web024713 STOCK Myl1 tm1(cre)Sjb /J These mice express cre recombinase from the skeletal muscle-specific myosin, light polypeptide 1 promoter. 024713 - Strain Details If you need … WebIn this case, we tested quadriceps and gastro- cnemius where cre expression driven by the Myl1-cre promoter has been shown to start at embryonic day 13.5 ( Bothe et al., … edwards v. aguillard 1987

Cre recombinase activity is inhibited in vivo but not ex vivo by a ...

WebAs in the case of the type II receptors, the Myl1-cre transgene significantly re- duced RNA levels for both Alk4 and Alk5 in muscle (SI Ap- pendix, Fig. S1). Targeting Alk4 or Alk5 in myofibers resulted in statistically significant effects on muscle mass, ranging from up to Table 1. Muscle weights WebWe characterized these CE strains using the Cre reporter mice, R26R (L) (acZ) , during embryogenesis and show that they direct tightly controlled tamoxifen-inducible reporter … Web9 apr. 2024 · For the second cross, the Myl1-cre produces recombination of both the Rosa26 - MEK1 and Mapk1f/f alleles in myofibers. These mice showed increased MEK1 expression and reduced ERK2 protein (bottom band) with a mild increase in ERK1 protein (top band, Figure 2D ). edwards v. aguillard oyez